Tissue Defect Reconstruction
Tissue loss can occur for many reasons, such as burns, traffic accidents, work accidents, diseases that impair wound healing and complications of surgery, and can range from isolated skin loss to the loss of a limb. Tissue loss can occur anywhere on the body. Different repair options are chosen depending on the size and depth of the lost tissue and its location.

When Is Tissue Loss Reconstruction Needed?
The aim of repairing tissue loss with plastic surgery methods is to help the tissue heal as well as possible while achieving a more balanced result in appearance and function. Plastic surgery repair methods may be needed in many different conditions.
Tissue loss after surgery
Tissue loss can occur after the removal of skin and soft tissue tumors. After wide tumor excisions, or after surgery in functional areas such as the face, hands and feet, repair with skin grafts or flaps may be needed. Cases in which we perform oncological reconstruction:
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Repair of defects after the removal of skin cancers (BCC, SCC)
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Head and neck tumors: in the treatment of tumors of the mouth, jaw and face
Breast Reconstruction (After Breast Cancer)
In women who have had part or all of a breast removed because of breast cancer, the breast can be recreated with plastic surgery methods. Reconstruction can be done in the same session as the cancer surgery (immediate) or after treatment is complete (delayed). The method is chosen by considering your body type, the amount of tissue removed, whether you will receive radiotherapy, and your own preference:
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Implant reconstruction: A tissue expander is often placed first; once the skin has stretched enough, it is replaced with a permanent implant.
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Reconstruction with your own tissue: The breast is reshaped using skin and fat taken from the back or abdomen.
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Nipple reconstruction and symmetry: In the final stage, the nipple and areola are created. If needed, the other breast is reduced or lifted for symmetry.
Loss of tissue integrity after trauma
Plastic surgery repair may be needed for skin and soft tissue injuries that cannot be closed edge to edge, or for tissue loss in functional areas. The repair technique is planned according to the location and size of the injury and the need to restore function. Common situations:
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Deep tissue loss after traffic accidents, falls or cut and puncture injuries
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Amputations or tissue loss caused by work accidents
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Soft tissue and bone loss caused by gunshot injuries
Burns and Infections
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Deep burns: Treatment and skin graft repair of burns that reach the deep layers of the skin and cause loss of function or deformity
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Infections (necrotizing fasciitis, etc.): Closure of large wounds after infections that rapidly destroy the skin and soft tissue
Chronic Wounds and Pressure Ulcers
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In paralyzed or bedridden people, pressure sores may need removal of the surrounding dead tissue and repair of the tissue loss.
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In people with diabetes, uncontrolled blood glucose levels and poor foot care can lead to wounds known as “diabetic foot”. These wounds are cared for and repaired with tissue repair techniques.
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Wounds caused by radiation damage can develop in areas treated with radiotherapy, and reconstruction may be needed.
→ Details: Wound care
Wound healing problems
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Scar revision may be needed for healing problems in wounds after surgery or trauma.
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After a wound heals, the scar tissue can harden or contract and limit movement; in this case, contracture release procedures may be needed.
Congenital Anomalies (Birth Defects)
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Congenital tissue deficiencies such as cleft lip and palate and facial clefts are repaired with methods specific to the area.
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Tissue repair techniques are used in some conditions with congenital tumors or fused tissues.

Nasal Defect Repair
→ Details: Skin cancer in the nose

Breast reconstruction with tissue expander
→ Details: Breast reconstruction

Post-injury skin grafting
→ Details: Skin grafting procedure

Hand flap application after burn trauma.
→ Details: Tissue loss in the hand

Methods Used in Tissue Loss Reconstruction
A personalized treatment plan is created by evaluating the location, size, depth and cause of the area that needs repair and any loss of function. Your general health, age and ability to follow the treatment are always considered when deciding on the extent of the surgery.
1) Skin Grafts
Transferring a thin piece of skin taken from one part of the body to another part to cover open wounds is called a skin graft. Skin grafts are classified by the thickness of the skin taken.
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Split-thickness skin graft: The top layer of the skin (epidermis) and part of the dermis are taken.
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Full-thickness skin graft: All layers of the skin (epidermis and dermis) are taken.
2) Flap repair
A flap is the transfer of skin together with the tissues beneath it, such as fat and muscle, to another area while preserving its own blood vessels.
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Local flaps: The wound is closed by moving neighboring tissue.
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Regional flaps: Tissue is moved from a nearby area while preserving its vascular pedicle.
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Free tissue transfer (microsurgery): The tissue is completely removed together with its blood vessels and connected to the vessels in the damaged area with microsurgical techniques.
3) Repairs with Tissue Expander
In areas without enough tissue, a silicone balloon is placed under the skin and gradually inflated to increase the amount of neighboring healthy tissue, which is then used for reconstruction. This method is preferred for scalp burns and breast reconstruction.
4) Tissue relaxation and deformation
Especially after burns, but also after trauma and surgery, wounds can heal abnormally, with thickening, pulling or contraction. Techniques that change the direction of the tissue, such as Z-plasty and W-plasty, can be used to release the tissue and change the direction of the scar.
5) Tissue engineering and cellular therapies
Artificial skin products (dermal matrices) and biological dressings are used to support tissue repair, especially in large burns or non-healing wounds. Stem cell therapies in this field are still largely at the research stage.

Surgery and Recovery
Minor repairs are usually performed under local anesthesia, and you go home the same day. Larger graft and flap surgeries are performed under general anesthesia in hospital; the hospital stay may last a few days, depending on the extent of the surgery. Some repairs are completed in one step, while for large tissue losses the treatment is planned in several stages. Before the surgery, we explain in detail which method we recommend, why, and what the recovery process will be like.
The recovery period varies from person to person and according to the surgery. Factors that determine recovery:
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The location and extent of the surgery
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Your general health
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The degree of functional impairment
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The need for rehabilitation
Risks of Tissue Defect Reconstruction
The risks vary depending on the location and size of the tissue defect, the extent of the surgery and individual characteristics. In general:
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Risks related to anesthesia
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General risks such as bleeding, infection and wound healing problems
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Graft or flap problems: failure of the skin graft to take or insufficient blood supply to the flap
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The need for corrective additional procedures or revision
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Asymmetry or contour irregularity
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Scarring
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Changes in sensation
Frequently Asked Questions
What is tissue loss reconstruction?
It is the surgical repair of tissue loss caused by trauma, burns, infection or surgery, in order to preserve function and appearance.
Is tissue loss reconstruction done the same way for everyone?
No. The repair is planned according to the size, depth and location of the loss, any accompanying tissue damage and the patient’s condition.
Can the breast be reconstructed after breast cancer surgery?
Yes. The breast can be recreated in the same session as the cancer surgery or after treatment is complete, using an implant or your own tissue. The method is planned together according to your body type and the treatments you receive.
What is the difference between a graft and a flap?
A graft is generally skin taken from another area and transferred to the recipient area. A flap is tissue that is moved while keeping its own blood supply.
Might I need another surgery after reconstruction?
In some cases, revision or additional reconstructive procedures may be needed; this possibility varies from person to person.
Will there be a scar after tissue loss reconstruction?
Every repair leaves a scar. However, we plan incisions along natural lines, choose the most suitable method and, with scar care, aim for the scar to fade significantly over time.
Is tissue loss reconstruction covered by insurance?
Because tissue loss reconstruction is a medical treatment, it may be covered by health insurance in many cases. Coverage depends on your policy; if you have insurance in your home country, check with your insurer before the surgery whether your policy covers this treatment in Türkiye.
Cost and Insurance
The cost of tissue loss reconstruction varies greatly from person to person depending on the extent of the repair. The main factors that determine the cost:
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The size, depth and location of the tissue loss
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The method used (stitches, skin graft, flap, tissue expander or microsurgery)
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The type of anesthesia (local or general)
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The length of the hospital stay
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Whether the treatment will be completed in one step or in several stages
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Whether additional treatments such as vacuum therapy and dressings are needed
Because tissue loss reconstruction is a medical rather than an aesthetic surgery, it may be covered by health insurance in many cases. Breast reconstruction after breast cancer is also considered part of the treatment. Coverage depends on your policy and your insurer’s agreements with hospitals. If you have insurance in your home country, we recommend checking with your insurer before the surgery whether your policy covers treatment in Türkiye. Once your treatment plan is clear after the consultation, we guide you through this process.
Information and Booking
Tissue loss often comes after an unexpected injury or a difficult course of treatment. Our aim is not only to close the wound, but to preserve your function and appearance as much as possible. At the consultation, we evaluate your condition together and plan the most suitable repair method step by step. If you live abroad, this also helps us plan your trip and your stay in Türkiye.
This page was prepared and reviewed by Op. Dr. Nurgül Altuntaş.
Last update: November 2026





